High doses carry the most psychological and physiological risk, so users should never exceed 15 mg/kg. Heavy, frequent use carries the possibility of neurotoxicity as well as the development of tolerance and psychological dependence. In users who are dependent, stopping DXM abruptly can result in withdrawal symptoms such as fatigue, apathy, flashbacks, constipation, insomnia, and anhedonia. Dextromethorphan (DXM) is a common component of combination cold medications that has become a popular drug of abuse for young adults.

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New Johns Hopkins StudyJohns Hopkins University School of Medicines has just published a new study on psychoactive effects of psilocybin. Guide to Magic Mushroom StrainsAre there different types of psilocybin? Read our guide to learn about the different magic mushroom strains and their individual effects. The length of a DXM trip is dose-dependent and depends on the form of DXM ingested. DXM hydrobromide typically lasts 4–8 hours, while DXM polistirex can last anywhere from 6–12 hours. Generally, DXM hydrobromide is the most popular recreational form.
Also tell them about any herbs, vitamins, and supplements you use. Dextromethorphan is a generic drug, which means it’s an exact copy of the active ingredient in a brand-name medication. The brand-name medications that dextromethorphan is based on are Delsym and Robitussin Long-Acting CoughGels. The Food and Drug Administration (FDA) approves dextromethorphan to help relieve coughing from a short-term cause.

What Are The Side Effects Of Dextromethorphan?

In particular, third and fourth plateau doses produce strong dissociative effects very similar to pre-anesthetic doses of ketamine. With that said, the DXM experience lasts longer, and generally produces more side effects, compared to ketamine. The following sections overview the physiological and psychological effects of DXM hydrobromide, the most commonly consumed form in recreational settings. DXM is dangerous to combine with other serotonergic substances. This includes monoamine oxidase inhibitors (MAOIs), selective serotonin reuptake inhibitors (SSRIs), and tricyclic antidepressants. DXM may also pose life-threatening reactions when taken with prescription and non-prescription antihistamines such as diphenhydramine and terfenadine.
Is DXM Safe?
Understanding these effects is crucial for addressing DXM addiction effectively. Early recognition and comprehensive treatment are essential for recovery. If you’re concerned about law enforcement getting involved, you don’t need to mention the substances used over the phone.
- A comprehensive and proactive approach significantly enhances the chances of successful long-term recovery.
- The FDA approved dextromethorphan for over-the-counter sale as a cough suppressant in 1958.
- Generic drugs are thought to be as safe and effective as the brand-name drug on which they’re based.
- You may have a raised risk of these side effects if you drink alcohol with dextromethorphan.
- At this dose, the effects feel much more similar to alcohol but with a pronounced reduction in cognitive function.
- Furthermore, a six-year retrospective review study conducted in California in 2008 showed a ten-fold increase in teen DXM addiction rates from 1999 to 2004.
What Are The Long-Term Health Effects Of DXM Addiction?
People who abuse drugs or alcohol may go to great lengths to hide the extent of their substance use. They may rationalize or explain their behaviors in ways that they hope will vindicate them. Typical recreational doses of DXM range from 250 mg to 1,500 mg, according to the Drug Enforcement Administration — which could amount to an entire bottle of extra-strength cough syrup. While all of these over-the-counter medications contain DXM, certain varieties of cold medications are specifically targeted for misuse and abuse. Laboratory tests involve analyzing biological samples to diagnose conditions or measure substance levels in the body. Laboratory tests may be ordered to detect the presence of DXM or other substances in the body.
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A household spoon is not an accurate measuring device and may cause you to take the wrong dose. Use the dosing cup provided with the product or ask your pharmacist to recommend an appropriate measuring device. Your pharmacist can tell you all of the ingredients in the specific dextromethorphan products they stock. This can be dangerous and lead to serious side effects, such as coma, psychosis, or death. Even extended drug tests don’t include it as their essential part.
Dextromethorphan (DXM) Addiction: Signs, Causes, Effects, And Treatment
Dextromethorphan misuse is dangerous, and there have been reports of fatal overdoses. Do not give dextromethorphan or any other medications to a pet unless your veterinarian recommends it. If your doctor confirms you’ve had a serious allergic reaction to dextromethorphan, they may have you switch to a different treatment.
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Healthcare providers begin by taking a detailed medical history to understand the patient’s use of DXM and any co-occurring medical or psychiatric conditions. This review includes questions about the frequency, dosage, and duration of DXM use, as well as any previous attempts to quit or reduce use. In high doses (plateaus 3 and 4) are very similar to the effects of ketamine.
During the 1960s and 1970s, dextromethorphan became available in an over-the-counter tablet form by the brand name Romilar. In 1973, Romilar was taken off the shelves after a burst in sales due to frequent abuse, and was replaced by cough syrup in an attempt to cut down on abuse. Prepare for a lot of euphoria and extreme heightening of senses and stimulation while also losing track of any concept of time. Truly you can run around and jump to the tunes of your favorite music for what feels like an hour and you can check the clock and see only 10 minutes have passed.
Other Ingredients
This is a big advantage to other cough suppressants that work by reducing muscle movement in the lungs. DXM reduces the threshold for coughing without affecting other important functions like ciliary movement (the tiny hairs in the lungs that clear out phlegm and bacteria). Any dose can lead to physical dangers such as heatstroke, respiratory depression (breathing that’s become too slow), or liver damage.

The lack of awareness about the dangers of DXM abuse further exacerbates this issue. To diagnose dextromethorphan (DXM) addiction, healthcare professionals evaluate the individual’s medical history reviews and physical exams using specific screening tools. According to the Mayo Clinic and the National Institute on Drug Abuse (NIDA), accurate diagnosis is crucial for effective treatment and recovery.
Dextromethorphan is an over-the-counter (OTC) cough suppressant used to relieve coughing caused by the common cold, flu, or other illnesses. Common side effects of dextromethorphan include dizziness, lightheadedness, drowsiness, sedation, nervousness, restlessness, confusion, nausea, vomiting, stomach pain, and constipation. Dextromethorphan is not addictive but has potential for abuse. Consult your doctor before taking dextromethorphan if pregnant or breastfeeding.
If you’ve become the victim of a DXM use disorder that you are struggling to kick and that’s negatively affecting your life and health, you’re not alone. Ketamine Treatment for Eating DisordersKetamine is becoming a promising treatment for various mental health conditions. Read to learn how individuals can use ketamine treatment for eating disorders. When DXM is consumed by itself and in moderation, the greatest dangers are acute psychological effects, including psychotic breaks, mania, agitation, prolonged dissociation, depression, and bad trips. In susceptible individuals, DXM can cause allergic reactions due to its histamine-releasing properties.